Utilize your Q skill to safely farm minions and poke enemies. Be careful when using Q to secure cannon minions, as opponents may try to block it.
While Dr. Mundo's base resistances are low, he scales incredibly well into the late game. Focus on consistent growth to become an unstoppable tank and damage dealer.
Mundo is weak against percentage health damage champions like Rhaast Kayn, Zac, and Aatrox. His long scaling time can also be a disadvantage in lower tiers.