For runes, prioritize Precision (PTA) and Sorcery (Manaflow Band, Gathering Storm) for early trades, late-game DPS, and mana sustain.
Build Kraken Slayer, Runaan's Hurricane, and Infinity Edge as core items, utilizing Hurricane's bolts to reduce your Q cooldown and efficiently stack souls.
Consider survivability items like Spirit Visage to significantly increase combat longevity and damage output, substituting Edge of Night or Death's Dance as needed.
Stats
Q
W
E
R