Tip
Keep your distance and avoid being hit by Ryze’s skills as well as being hit with Spell Flux(E) that rebound off minions. As Ryze can one-sidedly deal damage to you, pull lane and wait for him to overextend to gank him.
Singed vs Ryze

Keep your distance and avoid being hit by Ryze’s skills as well as being hit with Spell Flux(E) that rebound off minions. As Ryze can one-sidedly deal damage to you, pull lane and wait for him to overextend to gank him.